Xerostomia and dysgeusia in the elderly: prevalence of and association with polypharmacy

Xerostomia is defined as the perception of dry mouth, and dysgeusia, as a change in taste. Both are common complaints in the elderly, especially among those making use of polypharmacy drug combinations. Aim: This study aimed to determine the prevalence of xerostomia and dysgeusia and to investigate their association with polypharmacy in the elderly. Methods: older people under follow-up at the Multidisciplinary Elderly Center of the University Hospital of Brasília were interviewed and asked about health problems, medications used, presence of xerostomia and dysgeusia. Descriptive statistics were used to determine the prevalence of the symptoms surveyed. The chi-square test was used to investigate the relationship between xerostomia and dysgeusia and polypharmacy. Secondary associations were performed using binomial logistic regression. Results: Ninety-six older people were evaluated and of these, 62.5% had xerostomia and 21.1%, had dysgeusia. The average number of medications used was 4±3 medications per individual. Polypharmacy was associated with xerostomia but not dysgeusia. It was possible to associate xerostomia with the use of antihypertensive drugs. Conclusion: Xerostomia was a frequent complaint among elderly people making use of polypharmacy, especially those using antihypertensives. Antihypertensives and antidepressants were used most drugs by the elderly and exhibited interactions with drugs most prescribed in Dentistry. Two contraindications were found between fluconazole and mirtazapine; and between erythromycin and simvastatin

Prevalence of xerostomia and its association with systemic diseases and medications in the elderly: a cross-sectional study

ABSTRACT BACKGROUND: Dry mouth syndrome or xerostomia is defined as decreased salivary flow or hypofunction of salivary glands. Its origins are multicausal and might be the result of a change in the salivary glands or a systemic imbalance. OBJECTIVE: To ascertain the prevalence of self-reported xerostomia and to identify associated factors. DESIGN AND SETTING: Cross-sectional study on the entire population of 293 elderly people over 60 years of age living in a Brazilian municipality. METHODS: Data were gathered from a questionnaire that asked about demographic data, chronic diseases and use of continuous medications, and which used the Xerostomia Inventory (XI) to evaluate dry mouth sensation. Our analysis consisted of multivariate regression and estimation of odds ratios (OR) and their respective 95% confidence intervals (CI) in binary logistic regression models. RESULTS: The prevalence of self-reported xerostomia was 19.1%. Elderly people with diabetes had higher odds of having self-reported xerostomia (OR: 3.59; 95% CI: 1.48-8.68; P < 0.001) as did those who had chronic diseases and used continuous medication (OR: 2.3; 95% CI: 1.19-4.67; P = 0.009). Elderly people who used continuous medication for the gastrointestinal tract were more likely to have xerostomia (OR: 2.14; 95% CI: 1.03-1.44; P = 0.030). CONCLUSIONS: Elderly people with diabetes and chronic diseases who were using continuous medication were more likely to have dry mouth. Use of continuous medications for the gastrointestinal tract led to a greater chance of having self-reported xerostomia.

Prevalence of hyposalivation and associated factors in survivors of head and neck cancer treated with radiotherapy

Abstract Hyposalivation and sensation of dry mouth (xerostomia) are one of the most common adverse effects in the treatment of patients with head and neck cancer. Objective: This study evaluates the prevalence of late hyposalivation and associated factors in survivors of squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, or larynx treated with radiotherapy with or without concomitant chemotherapy. Methodology: A cross-sectional study was conducted with 88 patients who had concluded radiotherapy at least three months before the study, at a referral center for the treatment of head and neck cancer in the Southern region of Brazil. Hyposalivation was evaluated based on the stimulated salivary flow rate using the spitting method. Multivariate analysis using binary logistic regression was performed to determine the associations between hyposalivation and clinical and demographic variables. Results: Hyposalivation was found in 78.41% of the sample and the mean radiation dose was 63.01 Gy (±9.58). In the crude model of the multivariate analysis, hyposalivation was associated with higher doses of radiation (p=0.038), treatment with concomitant radiotherapy and chemotherapy (p=0.005), and time elapsed since the end of radiotherapy (p=0.025). In the adjusted model of the multivariate analysis, hyposalivation was only associated with dose and time elapsed. Patient who received higher doses of radiation had a 4.25-fold greater chance of presenting hyposalivation, whereas a longer time elapsed since the end of radiotherapy exerted a 75% protective effect against the occurrence of hyposalivation. Conclusion: Hyposalivation is a highly prevalence late-onset side effect of radiotherapy in patients treated for head and neck cancer, with a greater chance of occurrence among those who received higher doses of radiation and those who ended therapy less than 22 months before our study. Concomitant chemotherapy and radiotherapy does not seem to increase the chances of hyposalivation compared to radiotherapy alone.

Estudo da prevalência de alterações orais em uma população de pacientes diabéticos do estado da Paraíba / Study of the prevalence of oral changes in a population of diabetic patients in the state of Paraiba

Introdução: o Diabetes Mellitus (DM) atinge cerca de 425 milhões de pessoas no mundo. A cavidade oral pode se tornar susceptível ao surgimento de inúmeras alterações decorrentes do DM como xerostomia, infecções, queilites, alterações gengivais e periodontais. Objetivo: determinar a prevalência de alterações da cavidade oral em pacientes com DM. Material e Método: A amostra foi composta por 118 indivíduos com DM atendidos nas unidades básicas de saúde da família. As características clínicas dos pacientes foram analisadas com auxílio de espátula e iluminação artificial e registradas em um formulário previamente elaborado. Para a análise estatística foi considerado o valor de p<0,05 como significativo. Resultados: da amostra, 38 (32,2%) indivíduos eram do sexo masculino e 80 (67,8%) do sexo feminino, sendo a média de idade de 63,6 anos. O tipo 2 de DM foi o mais frequente (n=109/92,4%). Observou-se alta prevalência de alterações orais, destacando-se: a xerostomia, que exibiu associação com o uso de medicamentos (p=0,049) e a doença periodontal mais frequente em indivíduos com ≤ 60 anos (p<0,0001). A maioria dos indivíduos que fazia uso de hipoglicemiantes orais não apresentou a doença (77,8%; p=0,035). As lesões potencialmente malignas estiveram associadas com o sexo masculino (65,2%; p<0,0001) e com indivíduos de idade acima de 60 anos (82,6%; p<0,015). Conclusão: os indivíduos com DM apresentaram alta prevalência de alterações orais, destacando-se a xerostomia, doença periodontal e alterações potencialmente malignas sugerindo que o diabetes pode influenciar o desenvolvimento e/ou agravamento das doenças orais.(AU)

Introduction: Diabetes Mellitus (DM) affects about 425 million people worldwide. The oral cavity may become susceptible to the emergence of numerous changes from DM, such as xerostomia, infections, cheilitis, and gingival and periodontal changes. Objective: To determine the prevalence of oral cavity changes in patients with DM. Material and Method: The sample consisted of 118 individuals with DM assisted at basic family health units. The clinical characteristics of the patients were analyzed using an oral spatula and artificial lighting, and they were recorded on a form previously prepared. For the statistical analysis, the value of p <0.05 was considered significant. Results: From the sample, 38 (32.2%) individuals were men and 80 (67.8%) were women, with an average age of 63.6 years. Type 2 DM was the most frequent (n = 109 / 92.4%). There was a high prevalence of oral changes, namely xerostomia, which showed association with medication use (p = 0.049) and a higher frequency of periodontal disease in individuals aged ≤ 60 years (p <0.0001). Most of the individuals who used oral hypoglycemic agents did not present the disease (77.8%; p = 0.035). Potentially malignant lesions were associated with the male sex (65.2%, p <0.0001) and individuals over 60 years old (82.6%, p <0.015). Conclusion: Individuals with DM presented a high prevalence of oral changes, especially xerostomia, periodontal disease, and potentially malignant changes, suggesting that diabetes may affect the development and/or aggravation of oral diseases.(AU)

A Saúde bucal está associada à presença de sintomas depressivos em idosos? / Is oral health associated with the presence of depressive symptoms among the elderly?

Resumo O objetivo do estudo foi descrever a prevalência de sintomas depressivos medidos por meio da Escala de Depressão Geriátrica-EDG - 15 e testar a associação de variáveis de saúde bucal com sintomas depressivos em uma população de idosos vinculados a onze unidades de saúde da família do Sul do Brasil. Estudo transversal com 439 idosos. Foi utilizado questionário padronizado para a obtenção das variáveis socioeconômicas e de saúde bucal. As variáveis clínicas de saúde bucal foram obtidas por um dentista treinado. Os sintomas depressivos desfecho do estudo foram obtidos por meio da Escala de Depressão Geriátrica-EDG - 15. A prevalência dos sintomas depressivos foi de 18,3% (IC95% 14,6-21,8). Analisando as variáveis de exposição e os sintomas depressivos, por meio da análise regressão de Poisson ajustada, os indivíduos com 1 a 9 dentes (RP = 1,68; IC95%1,06-2,64, p = 0,012), com percepção de boca seca (RP = 2,23; IC95%1,52-3,28, p < 0,001) e de dor na boca (RP = 2,11; IC95% 1,10-4,07, p = 0,036) tiveram maiores prevalências de sintomas depressivos. O estudo identificou uma prevalência importante de sintomas depressivos e que as variáveis de saúde bucal estão associadas à presença dos mesmos na população idosa.

Abstract The scope of this study was to describe the prevalence of depressive symptoms measured by the Geriatric Depression Scale-EDG - 15 and test the association of oral health variables and depressive symptoms in a population of the elderly linked to eleven Family Health Units in the south of Brazil. It involved a cross-sectional study with 439 elderly individuals. A standardized questionnaire was used to obtain socio-economic and oral health variables of the study. The clinical variables of oral health were obtained by a qualified dentist. The symptoms of depression, which was the scope of the study, were obtained by the Geriatric Depression Scale-EDG −15. The prevalence of depressive symptoms was 18.3% (CI95% 14.6-21.8). Analyzing the exposure variables and depressive symptoms through adjusted Poisson regression analysis, individuals with 1 to 9 teeth (PR = 1.68; CI95% 1.06-2.64, p = 0.012), with a perception of dry mouth (PR = 2.23; CI95% 1.52-3.28, p < 0.001) and perception of pain in the mouth (PR = 2.11; CI95% 1.10-4.07, p = 0.036) have a higher prevalence of depressive symptoms. The study identified a significant prevalence of depressive symptoms and that oral health variables are associated with the presence of depressive symptoms in the elderly population.

Obesity, salivary glands and oral pathology / Obesidad, glándulas salivales y patología oral

Abstract Obesity has reached pandemic proportions in recent years. Not only adults suffer from the disease, but increasingly children and young people. One of the main causes of overweight and obesity is excessive food intake, in particular heavily processed carbohydrates. Obesity alters multiple organs, including the salivary glands, bringing functional alterations with it. Among researchers, the relation between obesity and tooth decay, periodontal disease and xerostomia is being debated. More and more scientific reports are drawing attention to the changes in the microflora of the oral cavity during obesity. All changes are closely related to the morphological and functional alterations of the salivary glands. This article review presents the current points of view regarding the impact of obesity on the health of the salivary glands, and how changes their functions influence other structures in the oral cavity.

Resumen La obesidad ha alcanzado proporciones pandémicas en los últimos años. No solo los adultos padecen la enfermedad, sino también cada vez más niños y jóvenes. Una de las principales causas del sobrepeso y la obesidad es la ingesta excesiva de alimentos, en particular los carbohidratos altamente procesados. La obesidad altera múltiples órganos, incluidas las glándulas salivales, y trae consigo alteraciones funcionales. Entre los investigadores, se está debatiendo la relación entre la obesidad y la caries dental, la enfermedad periodontal y la xerostomía. Cada vez más informes científicos están llamando la atención sobre los cambios en la microflora de la cavidad oral durante la obesidad. Todos los cambios están estrechamente relacionados con las alteraciones morfológicas y funcionales de las glándulas salivales. Esta revisión del artículo presenta los puntos de vista actuales sobre el impacto de la obesidad en la salud de las glándulas salivales, y cómo los cambios en sus funciones influyen en otras estructuras de la cavidad oral.

How common is dry mouth? systematic review and meta-regression analysis of prevalence estimates

Abstract The aim of this paper is to systematically review the literature to estimate the overall prevalence of xerostomia/hyposalivation in epidemiological studies. An electronic search was carried out up to February 2018 with no language restrictions. A total of 5760 titles were screened and just twenty-nine papers were included in review and the meta-analysis after a two independently reviewers applied the selection criteria. Data were extracted from PubMed and Web of Science databases. Eligibility criteria included original investigations from observational population-based studies that reported the prevalence of xerostomia or data that allowed the calculation of prevalence of xerostomia and/or hyposalivation. Studies conducted in samples with specific health conditions, literature reviews, case reports and anthropological studies, as conferences or comments were excluded. Sample size, geographic location of the study, study design, age of the studied population, diagnosis methods, and evaluation criteria used to determine xerostomia e/or hyposalivation were extracted for meta-analysis and meta-regression. Multivariate meta-regression analysis was performed to explore heterogeneity among studies. The overall estimated prevalence of dry mouth was 22.0% (95%CI 17.0-26.0%). Higher prevalence of xerostomia was observed in studies conducted only with elderly people. Despite diverse approaches to the condition's measurement, just over one in four people suffer from xerostomia, with higher rates observed among older people. Moreover, the measurement methods used currently may over- or underestimate xerostomia. These findings highlight the need for further work on existing and new clinical measure and will be useful to determine which one is more reliable in clinical and epidemiological perspectives.

Resumo O objetivo do estudo é revisar sistematicamente a literatura afim de estimar a prevalência global de xerostomia/hiposalivação em estudos epidemiológicos. Uma busca eletrônica foi conduzida até Fevereiro de 2018 sem restrições de linguagem. Um total de 5760 títulos foram inicialmente identificados e somente vinte e nove artigos foram incluídos na revisão e meta-análise após dois revisores independentes aplicarem os critérios de seleção. Os artigos foram extraídos das bases de dados PubMed/Medline e Web of Science. Os critérios de elegibilidade incluíram investigações originais de estudos observacionais de base populacional os quais reportaram a prevalência de xerostomia ou dados que permitissem o cálculo da prevalência de xerostomia e/ou hiposalivação. Estudos realizados em populações com condições de saúde específicas, revisões de literatura, relato de casos e estudos antropológicos, assim como, conferências ou comentários foram excluídos. Tamanho amostral, localização geográfica aonde foi realizado o estudo, desenho do estudo, idade da população estudada, métodos de diagnóstico e o critério de avaliação para determiner xerostomia e/ou hiposalivação foram extraídos para a meta-análise e metaregressão. Análise de meta-regressão multípla foi realizada para explorar a heterogeneidade entre os estudos. A prevalência global estimada de boca seca foi de 22.0% (95%IC 17.0-26.0%). Uma maior prevalência de xerostomia foi observada em estudos realizados exclusivamente em populações idosas. Apesar de diferentes abordagens utilizadas para mensurar as condições de interesse, cerca de uma em quatro pessoas é acometida por xerostomia, com taxas mais elevadas sendo observadas na população idosa. Além disso, os métodos de mensuração podem ter super- ou subestimado os valores de xerostomia. Os achados do presente estudo salientam a necessidade de mais estudos acerca das existentes e novas formas de avaliação clínica, os quais serão úteis para determinar qual é a mais confiável para as perspectivas clínicas e epidemiológicas.

Prevalence of oral lesions and chronic non-communicable diseases in a sample of chilean institutionalized versus non-institutionalized elderly

Chile is experiencing a process of demographic aging with an increase in the number of elderly people, a percentage of which resides in long-term establishments for the elderly (LEE). however, there is little information on the reality of the elderly in these long-term care facilities, so this study was conducted to compare the epidemiological profile of the prevalent oral pathologies as well as chronic non-communicable diseases (NCDs), of institutionalized versus non-institutionalized elderly subjects. seventy-six institutionalized and forty-three non-institutionalized subjects were examined intraorally, and their clinical health record, gender and age were obtained, according to inclusion/exclusion criteria. the results indicate that female gender is the most common, with an average age of 78.5 year, with those 80 years old and above comprising the predominant group. the most prevalent oral lesions within the institutionalized group were denture stomatitis and irritative hyperplasia, while in the non-institutionalized these two lesions were found less frequently. as for the presence of xerostomia, there was no difference between the groups. the most common condition in both groups was total maxillary and mandibular edentulous, with the latter variable present more frequently in the institutionalized group (p<0.05). the predominant NCD for both groups were arterial hypertension, arthritis-osteoarthritis and diabetes mellitus (p>0.05), and depression was the most prevalent NCD in the non-institutionalized group (p<0.05). this study provides valuable information on the epidemiology of elderly´s oral lesions and NCDs to inform the decision-making process of public health policies.

Manifestaciones bucales relacionadas con el diagnóstico de enfermedades reumáticas / Oral manifestations related to the diagnosis of rheumatic diseases

Introducción: las enfermedades reumáticas se caracterizan por presentar una amplia gama de manifestaciones sistémicas. Sin duda alguna, la cavidad bucal es asiento de muchas de ellas, que incluso llegan a formar parte de los criterios diagnósticos de estas enfermedades. Objetivo: exponer las consideraciones sobre la relación existente entre afecciones bucales y enfermedades reumáticas. Métodos: se realizó una revisión sobre la relación entre afecciones reumáticas y manifestaciones bucales en Internet. La búsqueda abarcó artículos publicados en los últimos 5 años. Se evaluaron revistas de impacto de la Web of Sciencies, Scopus, Redalyc y Latindex relacionadas con el tema (37 revistas). Se consultaron las bases de datos de sistemas referativos, como MEDLINE, PubMed y SciELO con la utilización de varios descriptores tanto en inglés como en español. Se incluyeron artículos en idioma inglés, portugués y español. Se obtuvieron 77 artículos, se circunscribió el estudio a 49 que enfocaron esta temática de manera más integral. La revista que mayor representatividad del tema tuvo fue la Revista Cubana de Reumatología con 24,67 por ciento del total de artículos, el resto de las revistas se comportaron de manera uniforme. Análisis e integración de la información: existe estrecha relación entre las enfermedades bucales y las afecciones reumáticas. En ocasiones, las manifestaciones bucales constituyen criterios diagnósticos de las enfermedades reumáticas; las úlceras bucales, la xerostomía, la gingivitis y la afectación de la articulación temporomandibular son las de mayor incidencia. Conclusiones: las manifestaciones bucales pueden ser expresión del desorden reumático, pero también pueden inducir su aparición o ser los causantes de su descompensación. La presencia de procesos infecciosos así como la utilización de medicamentos con acción inmunosupresora y/o inmunomoduladora, son elementos que refuerzan aun más esta relación(AU)

Introduction: rheumatic diseases are characterized by a wide range of systemic manifestations. The oral cavity is home to many of these manifestations, which may even constitute diagnostic criteria for those diseases. Objective: describe the relationship existing between oral disorders and rheumatic diseases. Methods: a review was conducted on the Internet about the relationship between rheumatic diseases and oral manifestations. The search included papers published in the last five years. An evaluation was performed of high impact journals from the Web of Sciences, Scopus, Redalyc and Latindex which dealt with the subject (37 journals). Databases from reference systems such as MEDLINE, PubMed and SciELO were consulted with the aid of various search terms in English and Spanish. The papers included were in English, Portuguese and Spanish. Of the 77 papers obtained, the reviewers selected the 49 which approached the study subject in a more comprehensive manner. The journal with the highest presence of the topic was the Cuban Journal of Rheumatology, with 24.67 percent of the total papers. The remaining papers were evenly distributed among the other journals. Data analysis and integration: there is a close relationship between oral diseases and rheumatic conditions. Oral manifestations sometimes constitute diagnostic criteria for rheumatic diseases. Among the most common of these are mouth ulcers, xerostomia, gingivitis and temporomandibular joint disorders. Conclusions: oral manifestations may be the expression of rheumatic disorders, but they may also induce their emergence or be responsible for their decompensation. The presence of infectious processes, as well as the use of drugs with an immunosuppressive and/or immunomodulatory action, may further strengthen this relationship(AU)

Risk factors, hyposalivation and impact of xerostomia on oral health-related quality of life

Abstract To determine xerostomia-related frequency, factors, salivary flow rates and Oral Health-Related Quality of Life (OHRQoL) of patients attending the Universidad Andrés Bello Dental School Clinic, in the city of Viña del Mar, Chile. The study involved 566 patients assessed with xerostomia, based on a single standardized questionnaire. The severity and impact of xerostomia on OHRQoL was assessed using a visual analogue scale (VAS) and the short version of the Oral Health Impact Profile Questionnaire (OHIP-14sp), respectively. Stimulated and non-stimulated salivary flow rates were obtained from a sample of patients. Xerostomia was reported in 61 patients (10.8%), comprising 50 women (83.3%) and 11 men (16.7%) (p < 0.013). The prevalence was 13% among the women and 6.1% among the men. Gender, age and medication were found to be independent risk factors for the development of xerostomia. Hyposalivation was found in 10 of the 35 patients with xerostomia (28.6%) and in 2 patients without it (p < 0.011). Patients with xerostomia had a reduced OHRQoL, compared with patients without xerostomia, as shown by the total OHIP-14sp score (p < 0.001). Xerostomia was a common, potentially debilitating condition with a major impact on the OHRQoL of a patient population attending a university-based dental clinic. Hyposalivation was present in almost 30% of the patients who complained of xerostomia. It is important that general dentists be aware of this condition, so that they can provide patients with a good diagnosis, treatment and follow-up.

Distribuição espacial da xerostomia e índice de exclusão social de idosos de Piracicaba, SP / Spatial distribution of xerostomia and social exclusion index of elderly patients in Piracicaba, SP, Brazil

Objetivo: Analisar o padrão de distribuição espacial dos casos de xerostomia em idosos residentes em Piracicaba, SP. Material e Métodos: Estudo ecológico de análise espacial dos casos de xerostomia avaliados durante a campanha de prevenção e diagnóstico precoce do câncer bucal no ano de 2012. Foram analisadas a taxa média de prevalência anual e a intensidade e significância dos aglomerados pelos índices de Moran global, MoranMap e LISAMap. Resultados: A prevalência de xerostomia em idosos foi de 17,42% e a taxa de autorrelato de xerostomia anual média foi de 3,18 casos/bairro sendo que os bairros: Mário Dedini (20,76 casos), Jardim São Jorge (14,28 casos) e Jardim Itapuã (10,61 casos) foram os que registraram as maiores taxas. O índice de Moran global foi de -0,317 (p < 0,04), ou seja, existe uma correlação espacial significativa e esta é inversa. Houve formação de clusters nos bairros da região Sul e Oeste. Conclusão: Em Piracicaba, o padrão de distribuição espacial da xerostomia, com formação de clusters, indica onde se deve priorizar os esforços em saúde bucal para os idosos.Descritores: Inquéritos de saúde bucal. Xerostomia. Idoso.

Alzheimer’s disease: oral manifestations, treatment and preventive measures / Enfermedad de Alzheimer: manifestaciones orales, tratamiento y medidas preventivas

In the treatment of patients with dementia Alzheimer's type non-current and are facing tough situations. Treatment should be tailored to each stage of the disease and for each patient. In this type of disease is very important to involve families and caregivers to improve the quality of life of patients. The main goal with these patients is prevention. Patients should be all oral manifestations caused by the lack of inadequate oral hygiene, xerostomia and manifestations derived by taking drugs. The aim of this review is to describe the main oral manifestations that can result from this disease and the best treatment options taking into account the clinical stages in which patients are found.

En el tratamiento a pacientes con demencias tipo Alzheimer se afrontan situaciones infrecuentes y comprometidas. El tratamiento debe personalizarse para cada estadio de la enfermedad y para cada paciente. En este tipo de enfermedades es muy importante involucrar a los familiares y cuidadores para mejorar la calidad de vida del enfermo. El principal objetivo con estos pacientes es la prevención. Se deben controlar todas las manifestaciones orales provocadas por la falta de una inadecuada higiene oral, la xerostomía y las manifestaciones derivadas por los fármacos que consumen. El objetivo de esta revisión es describir cuáles son las principales manifestaciones orales que pueden derivar de esta enfermedad y las mejores opciones de tratamiento teniendo en cuenta las etapas clínicas en las que se encuentran los pacientes.

Interfaces between bariatric surgery and oral health: a longitudinal survey / Interface entre cirurgia bariátrica e saúde bucal: estudo longitudinal

PURPOSE: To evaluate oral changes, such as dental caries, periodontal disease, dental wear and salivary flow in bariatric patients. Fifty four obese patients who underwent bariatric surgery were studied before (n=54), up after 3 months (n=24) and 6 months (n=16). METHODS: Indices for evaluating oral conditions were: DMFT, CPI, DWI and salivary flow. OIDP questionnaire was used to assess the impact of oral health on quality of life. ANOVA and Spearman correlation were used (p<0.05). RESULTS: DMFT was 17.6±5.7, 18.4±4.1 and 18.3±5.5 (P>0.05), presence of periodontal pockets in 50 percent, 58 percent and 50 percent of patients (p>0.05), tooth wear in dentin present in 81.5 percent, 87.5 percent and 87.5 percent before, 3 and 6 months after surgical treatment respectively. There were differences between the three periods for prevalence and severity of dental wear (p = 0.012). Salivary flow was 0.8±0.5 ml/min before surgery, 0.9±0.5 ml/min for 3 months and 1.1±0.5m/min for 6 months (p>0.05). The impact of oral health on quality of life decreased with time after bariatric surgery (p= 0.029). CONCLUSION: The lifestyle changes after bariatric surgery and these changes may increase the severity of pre-existing dental problems. However, these alterations in oral health did not influence the quality of life.

OBJETIVO: Avaliar alterações bucais, como cárie dentária, doença periodontal, desgaste dentário e fluxo salivar, em pacientes bariátricos. MÉTODOS: Cinquenta e quatro pacientes obesos, submetidos à cirurgia bariátrica, tiveram suas condições bucais avaliadas antes (n=54), aos 3 meses (n=24) e aos 6 meses (n=16) após a cirurgia bariátrica. Os índices para avaliação das condições bucais foram: CPOD, IPC, IDD e o volume de fluxo salivar. O questionário OIDP foi utilizado para verificar o impacto da saúde bucal na qualidade de vida. ANOVA e correlação de Spearman foram utilizados para análise estatística (p<0,05). RESULTADOS: CPOD foi 17,6±5,7, 18,4±4,1 e 18,3±5,5 (p>0,05), bolsa periodontal foi encontrada em 50 por cento, 58 por cento e 50 por cento dos pacientes (p>0,05) e o desgaste dentário em dentina em 81,5 por cento, 87,5 por cento e 87,5 por cento dos pacientes, respectivamente antes, 3 meses e 6 meses após a cirurgia bariátrica. Houve diferença significativa entre os três períodos estudados, quanto à prevalência e à severidade do desgaste dentário (p=0,012). O fluxo salivar foi 0,8±0,5 ml/min antes, 0,9±0,5 ml/min aos 3 e 1,1±0,5 ml/min aos 6 meses após cirurgia (p>0,05). O impacto da saúde bucal na qualidade de vida diminuiu com o tempo decorrido após cirurgia bariátrica (p=0,029). CONCLUSÕES: As mudanças no estilo de vida após a cirurgia bariátrica podem aumentar a gravidade de problemas bucais pré-existentes. Entretanto, esta alteração na condição bucal pode não influenciar a qualidade de vida.

Xerostomía y uso de medicamentos en adultos / Xerostomia and the use of drugs in adults

OBJETIVO: determinar la prevalencia de xerostomía en relación con el uso de medicamentos en los adultos de 20 años y más del Consultorio Médico 64-02 de Guanabacoa, de julio a diciembre del año 2007. MÉTODOS: se realizó un estudio descriptivo y se utilizó muestreo bietápico. La presencia de xerostomía, basada en definición utilizada por otros autores, se determinó con 3 preguntas, además: edad, sexo, uso, cantidad y tipos de medicamentos, según cuestionario. RESULTADOS: se procesó la información en Excel, utilizando el porcentaje para resumirla. Los resultados se presentan en tablas. Se relacionaron las variables, con la X² y diferencia de proporciones (p<0,05), con el programa Epidat. De 511 individuos estudiados, 176 (34,4 por ciento) percibieron xerostomía. El sexo femenino fue el más afectado, se incrementa con la edad, fue mayor en el grupo de 60 años y más. CONCLUSIONES: los medicamentos más utilizados fueron: antihipertensivos y antiasmáticos. Todos los que usaron hipoglicemiantes y antialérgicos, percibieron xerostomia, y se incrementó según el número de medicamentos usados(AU)

OBJECTIVE: to determine the prevalence of xerostomia in connection with the use of drugs in adults aged 20 and over at the Family Physician's office 64-02 in Guanabacoa from July to December 2007. METHODS: a descriptive study was undertaken and a bistage sampling was used. The presence of xerostomia based on the definition used by other authors was determined by 3 questions in addition to age, sex, use, amount and type of drugs according to the questionnaire. RESULTS: the information was processed in Excel, using percentage to resume it. The results were presented in tables. The variables were related to X2 and the difference of proportions (p<0.05) by using the Epidat program. Of 511 studied individuals, 176 (34.4 percent) perceived xerostomia. Females were the most affected. It increases with age, and the group aged 60 and over was the most affected. CONCLUSIONS: the most used drugs were the antihypertensive and antiasthma drugs. All those who took glycemia-lowering and antiallergic drugs perceived xerostomia and it rose according to the number of drugs used(AU)

Estudio clínico epidemiológico de xerostomia en adultos mayores desdentados totales / Clinical epidemiological study of xerostoma in eldery totally edentulous

Introducción y objetivo: Debido al aumento de la población anciana en nuestra sociedad, aquejada por disminución variable del flujo salival, influyendo en su calidad de vida, el objetivo de este trabajo fue analizar la prevalencia de la disminución salival y xerostomÍa en relación con distintos factores causales.Materiales y métodos: A 126 individuos edén tul os , mayores de 50 años de edad (x 62,41 ::1:::8,24), de ambos sexos, se realizó una historia clínica diseñada al efecto, registrando los factores locales y generales predisponentes. Los resultados se analizaron estadísticamente (p< 0,05). Resultados: 40,5% presentó xerostomía, con mayor cantidad de casos a mayor edad y sexo femenino, con diferencias significativas en mujeres de 60 a 69 años de edad. El 34,9% estaba aparentemente sano y e165,1 % padecía una o más enfermedades sistémicas y el 53,3% usaba cotidianamente medicación (x 2,14::1::: 1,10 drogas diarias).Discusión: Escaso flujo salival y sensación de sequedad oral se relacionaron con problemas médicos y uso de medicamentos, con diferencias significativas. El estudio mostró al aumento de la edad y el sexo femenino como factores en la disminución del flujo salival y xerostomía, pudiendo ser afectado por la edad, los enfermedades y/ o la medicación, que se acentúan con la edad. Conclusiones: La xerostomía no es una enfermedad sino una manifestación clínica de sensación de sequedad oral con o sin hiposialia. De etiología diversa, al ser identificada permite un plan de tratamiento que deberán proyectar juntos distintos profesionales de la salud.

Introduction: Because of an increasing number of older people in our community presenting with a variable decrease of salivary flow which affects their quality of life, we aimed to analyze the prevalence of salivary decrease and xerostomia in relation to various causing factors. Purpose.-The objective of this study was to analyze the prevalence of a decrease of normal salivary secretion and xerostomia in relation to various factors in the older population of our community. Material and method.- One hundred and twenty-six edentulous male and female subjects older than 50 years (62.41 8,24) were entered . A chart was specially designed for this study where both local and general predisposing factors were...

Frequency of subjective dry mouth and burning mouth syndrome in elder residents of sanitariums in Tehran, 2005

Xerostomia and burning mouth syndrome are two relatively common complaints mostly encountered during adult age. They may have a great impact on the quality of life and become a serious health problem for patients. This study was designed to determine the frequency of subjective dry mouth and butting mouth syndrome [BMS] in elder residents of sanitariums in Tehran. In this cross-sectional investigation, the study group consisted of elderly adults [65 years and over], residing in twenty seven of the 36 sanitariums in Tehran. 499 volunteers [308 women and 191 men] underwent medical examination. Diagnosis was based on the patients' complaints of both subjective dry mouth [SDM] and BMS. No obvious oral lesion was detected in the BMS cases. 124 [24.8%] individuals were classified as having subjective oral dryness and BMS. SDM and BMS were seen in 121[242%] and 39 [7.8%] of the 499 cases, respectively. A statistically significant difference was observed between women [27.9%] and men [18.3%] with SDM [P=0.026], but not BMS [9.1% female, 5.8 male]. Subjective dry mouth and burning mouth syndrome are relatively frequent problems in elderly residents of sanitariums in Tehran. A higher percentage of females are involved as compared to males

Levantamento epidemiológico de cárie dentária e sua correlação com fluxo salivar em crianças de 5-6 anos / Epidemiological survey on dental caries and its correlation with the salivary flow in 5-6 year-old children

Introdução - Embora muitas doenças bucais sejam multifatoriais, existem algumas correlações que favorecem seu aparecimento. Este estudo objetivou correlacionar a prevalência de cárie dentária e a alteração no fluxo salivar de crianças na faixa de idade 5-6 anos (n= 151), da EMEI Vera Savi, em Bauru-SP, considerando a importância de um fluxo salivar normal para a manutenção das condições saudáveis da boca. Métodos - Foi realizado um levantamento epidemiológico de cárie dentária, utilizando-se o índice CPOD e ceod, e o fluxo salivar foi analisado por meio de coleta de saliva .estimulada, nos participantes da pesquisa. Resultados - O ceod médio foi de 2,67 e o CPOD foi de 0,10, sendo que 65,57% da crianças apresentaram experiência de cárie e 34,43% estavam com necessidade de tratamento de alta complexidade. Foi encontrada redução no fluxo salivar em 50,42% dos pré-escolares e demonstrou-se que esse fator etiológico foi de alta prevalência. Entre os pré-escolares que apresentaram redução no fluxo salivar, 9,25% eram xerostômicos e 41,17% tinham baixo fluxo salivar. Conclusão - Não foi observada diferença estatística entre o baixo fluxo salivar e o aumento da prevalência de cárie dentária, isoladamente, mas demonstrou uma tendência nesta correlação, havendo necessidade de novos estudos, analisando outros fatores de risco para se chegar a uma conclusão menos transitória.

Introduction - Even though a lot of dental diseases have been considered multicause, there are some that promote its occurrence. The aim of this work was to correlate dental caries prevalence and reduction of salivary flow in children aged 5 to 6 years old (n= 151), students of EMEI Vera Savi, city of Bauru- SP; considering the importance of normal salivary flow to the maintenance of health conditions into the oral cavity. Methods - An epidemiological research on dental caries was carried out using the DMFT and dmft indices, and the salivary flow was analyzed on stimulated saliva, in the research participants. The mean dmft was 2.67 and the DMFT was 0.10, considering that 65.57% of the children presented dental caries and 34.43% needed high complexity treatment. Results - The results showed a salivary flow reduction in 50.42% of the preschool children and indicated that this etiological factor was of high prevalence. Among the children with salivary flow reduction, 9.25% were xerostomic and 41.17% had low salivary flow. Conclusion - Statistical differences between the low salivary flow and the increase of dental caries prevalence were not observed singly, but showed propitious tendency in this correlation, suggesting the necessity of new studies, taking other risk factors into account in order to get a better conclusion.